Lacosamide
High-quality chemical supplied by Jinan Shenghe Chemical Co., Ltd. Competitive pricing, reliable delivery, and full technical support for B2B buyers worldwide.
Specifications
| Molecular Formula | C13H18N2O3 |
|---|---|
| Molecular Weight | 250.2936 |
| Boiling Point | 536.4°C at 760 mmHg |
| Flash Point | 278.2°C |
| Vapor Pressure | 1.4E-11mmHg at 25°C |
Detailed Chemical Properties & Synonyms
Deskripsi
Lacosamide · CAS 175481-36-4 · C13H18N2O3. UNII 563KS2PQY5. Titik Didih: 536.447; Titik Leleh: 140-146˚C; Kelarutan: 10-33.3 g/L.
Identifikasi
| Nomor Registrasi CAS | 175481-36-4 |
|---|---|
| PubChem CID | 219078 |
| Rumus molekul | C13H18N2O3 |
| Nama IUPAC | (2R)-2-acetamido-N-benzyl-3-methoxypropanamide |
| UNII (FDA) | 563KS2PQY5 |
Deskriptor Terhitung
| Berat Molekul | 250.29 |
|---|---|
| XLogP3 | 0.3 |
| Jumlah Donor Ikatan Hidrogen | 2 |
| Jumlah Akseptor Ikatan Hidrogen | 3 |
| Jumlah Ikatan yang Dapat Berputar | 6 |
| Massa Eksak | 250.13174244 |
| Massa Monoisotopik | 250.13174244 |
| Luas Permukaan Polar Topologi | 67.4 |
| Jumlah Atom Berat | 18 |
| Muatan Formal | 0 |
Sifat Fisika & Kimia
| Titik Didih | 536.447 |
|---|---|
| Titik Leleh | 140-146˚C |
| Kelarutan | 10-33.3 g/L |
| LogP | 0.728 |
Deskripsi fisik & catatan penanganan
- Lacosamide is an antiepileptic drug with high oral potency, stereoselectivity, and anticonvulsant effects. By blocking sensory neuronal voltage-gated sodium channels that mediate neuropathic pain responses, lacosamide was shown to possess analgesic activity. Lacosamide is a chiral functionalized amino acid. The S-stereoisomer does not exhibit antiepileptic activity.
Status Regulasi
| Ringkasan notifikasi GHS | 1.5% (1 / 66) |
|---|
Klasifikasi Bahaya GHS
| Ringkasan notifikasi GHS | 1.5% (1 / 66) |
|---|---|
| Pernyataan bahaya yang dilaporkan | H301 (93.9%), H319 (93.9%) |
Bahan kimia ini tidak memenuhi kriteria bahaya GHS untuk 1.5 % (1 dari 66) laporan.
H301 (93.9%): Toksik jika tertelan [Bahaya Toksisitas akut, oral]
Penggunaan yang Terdokumentasi
- Use (kg; approx.) in Germany (2009): >250
- Consumption (g per capita; approx.) in Germany (2009): 0.00305
- In the US and Europe, lacosamide is indicated for the treatment of partial-onset seizures in children and adults. In Canada, it is reserved for use in adults. It is also used as an adjunctive therapy in the treatment of primary generalized tonic-clonic seizures in patients four years of age and older. The extended-release capsules of lacosamide are indicated for the treatment of partial-onset seizures in adults and in pediatric patients weighing at least 50 kg.
- Lacosamide is an amino acid derivative with a unique anticonvulsant activity that is used in combination with other agents as therapy of partial onset seizures. Lacosamide therapy is associated with a low rate of transient serum enzyme elevations and has been linked to rare instances of clinically apparent liver injury.
- Breast Feeding; Lactation; Milk, Human; Anticonvulsants
- Lacosamide (Class: Other Substances, Added Date: 06-2010)
Sinonim
Lacosamide; 175481-36-4; Erlosamide; Vimpat; Harkoseride; SPM 927; SPM-927; (r)-lacosamide 1; MOTPOLY; Lacosamida; DTXSID1057666; ADD 234037; 563KS2PQY5; SPM927; Propanamide, 2-(acetylamino)-3-methoxy-N-(phenylmethyl)-, (2R)-; ADD243037
Pertanyaan yang Sering Diajukan
Apa nomor CAS dan rumus molekul dari Lacosamide?
CAS 175481-36-4; rumus molekul C13H18N2O3; berat molekul — g/mol.
Dengan nama lain apa Lacosamide dikenal?
Lacosamide, 175481-36-4, Erlosamide, Vimpat, Harkoseride, SPM 927.
Apakah Lacosamide diklasifikasikan sebagai berbahaya?
1.5 % notifikasi GHS tidak melaporkan klasifikasi bahaya (1 dari 66).
Apa sifat fisik utama dari Lacosamide?
Titik Didih: 536.447; Titik Leleh: 140-146˚C; Kelarutan: 10-33.3 g/L; LogP: 0.728.
Data pada halaman ini diambil dari PubChem (US National Library of Medicine) dan Wikidata. Data spesifik per grade — kadar, kelembapan, ukuran partikel, kemasan, masa simpan — diterbitkan per batch pada COA dan tidak dipublikasikan di sini.
Packaging & Shipping
- Standard: 25 kg fiber drum / 200 kg steel drum with double PE liner
- Small pack: 1 kg / 5 kg aluminum foil bag for lab & sample
- Custom: packaging size and labeling per customer requirement
- Lead time: in-stock items ship within 3-5 business days
- Documents: COA, MSDS / SDS, TDS provided with every shipment
- Global: air, sea (FCL / LCL) and express to 80+ countries
Storage & Handling
Store in a cool, dry, well-ventilated place away from heat, direct sunlight and incompatible materials. Keep container tightly closed. Use appropriate personal protective equipment and refer to the SDS for full safety guidance before handling.
Frequently Asked Questions
Yes. A batch-specific COA and free or charged sample are available on request before bulk ordering.
Yes. We offer custom grade, particle size and purity adjustment based on your application and order volume.
MOQ depends on the product; small quantities are supported for R&D and trial runs.
Every batch is tested in-house and retains full traceability from raw material to finished goods.
Why Choose Jinan Shenghe Chemical
Request a Quote
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About Jinan Shenghe Chemical Co., Ltd.
Jinan Shenghe Chemical Co., Ltd.
We are a professional chemical supplier based in Jinan, China. Since 2013, we have been connecting manufacturers and global B2B buyers with reliable sourcing, quality-controlled products and efficient logistics.
Our business covers food & feed additives, fine chemicals, pharmaceutical intermediates, eco-materials, coatings and specialty chemicals — all non-hazardous and compliant with our licensed scope.