Telithromycin
High-quality chemical supplied by Jinan Shenghe Chemical Co., Ltd. Competitive pricing, reliable delivery, and full technical support for B2B buyers worldwide.
Specifications
| Molecular Formula | C65H84ClN5O13 |
|---|---|
| Molecular Weight | 1178.8412 |
| Boiling Point | 966.2°C at 760 mmHg |
| Flash Point | 538.2°C |
| Vapor Pressure | 0mmHg at 25°C |
Detailed Chemical Properties & Synonyms
Deskripsi
Telithromycin · CAS 191114-48-4 · C43H65N5O10. UNII KI8H7H19WL. Titik Leleh: 176-188 °C; Titik Leleh: 187-188 °C; Kelarutan: 300.
Identifikasi
| Nomor Registrasi CAS | 191114-48-4 |
|---|---|
| PubChem CID | 3002190 |
| Rumus molekul | C43H65N5O10 |
| Nama IUPAC | (1S,2R,5R,7R,8R,9R,11R,13R,14R)-8-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-15-[4-(4-pyridin-3-ylimidazol-1-yl)butyl]-3,17-dioxa-15-azabicyclo[12.3.0]heptadecane-4,6,12,16-tetrone |
| UNII (FDA) | KI8H7H19WL |
Deskriptor Terhitung
| Berat Molekul | 812.0 |
|---|---|
| XLogP3 | 4.2 |
| Jumlah Donor Ikatan Hidrogen | 1 |
| Jumlah Akseptor Ikatan Hidrogen | 13 |
| Jumlah Ikatan yang Dapat Berputar | 11 |
| Massa Eksak | 811.47314329 |
| Massa Monoisotopik | 811.47314329 |
| Luas Permukaan Polar Topologi | 172 |
| Jumlah Atom Berat | 58 |
| Muatan Formal | 0 |
Sifat Fisika & Kimia
| Titik Leleh | 176-188 °C |
|---|---|
| Titik Leleh | 187-188 °C |
| Kelarutan | 300 |
Deskripsi fisik & catatan penanganan
- White to off-white crystalline powder
- Crystals from ether
- 278.01 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
- 272.03 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
- 269.7 Ų [M+H]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]
- Oral: Tablets 400 mg (Ketek), (Aventis).
Klasifikasi Bahaya GHS
| Pernyataan bahaya yang dilaporkan | H318 (66.7%), H362 (66.7%), H370 (33.3%), H400 (33.3%), H410 (66.7%) |
|---|
H318 (66.7%): Menyebabkan kerusakan mata serius [Bahaya Kerusakan mata serius/iritasi mata]
H362 (66.7%): May cause harm to breast-fed children [Reproductive toxicity, effects on or via lactation]
Penggunaan yang Terdokumentasi
- Use (kg; approx.) in Germany (2009): >75
- Consumption (g per capita; approx.) in Germany (2009): 0.000916
- For the treatment of <i>Pneumococcal</i> infection, acute sinusitis, acute bacterial tonsillitis, acute bronchitis and bronchiolitis, lower respiratory tract infection and lobar (pneumococcal) pneumonia.
- Preperation: C. Agouridas et al., EP 680947; eidem, US 5635485 (1995, 1997 both to Roussel Uclaf)
- For the treatment of Pneumococcal infection, acute sinusitis, acute bacterial tonsillitis, acute bronchitis and bronchiolitis, lower respiratory tract infection and lobar (pneumococcal) pneumonia.
- Telithromycin is a ketolide, a novel form of macrolide antibiotic that is recommended for treatment of community acquired pneumonia. Telithromycin was approved for use in the United States in 2004 and subsequently linked to several cases of severe drug induced liver injury.
Sinonim
Telithromycin; Ketek; 191114-48-4; HMR-3647; HMR3647; Levviax; RU-66647; telithromycine; telitromicina; DTXSID3046455; KI8H7H19WL; NSC-758940; DTXCID1026455; RU66647; telithromycinum; RefChem:56921
Pertanyaan yang Sering Diajukan
Apa nomor CAS dan rumus molekul dari Telithromycin?
CAS 191114-48-4; rumus molekul C43H65N5O10; berat molekul — g/mol.
Dengan nama lain apa Telithromycin dikenal?
Telithromycin, Ketek, 191114-48-4, HMR-3647, HMR3647, Levviax.
Apakah Telithromycin diklasifikasikan sebagai berbahaya?
Pernyataan bahaya yang dilaporkan: H318, H362, H370, H400, H410.
Apa sifat fisik utama dari Telithromycin?
Titik Leleh: 176-188 °C; Titik Leleh: 187-188 °C; Kelarutan: 300.
Data pada halaman ini diambil dari PubChem (US National Library of Medicine) dan Wikidata. Data spesifik per grade — kadar, kelembapan, ukuran partikel, kemasan, masa simpan — diterbitkan per batch pada COA dan tidak dipublikasikan di sini.
Packaging & Shipping
- Standard: 25 kg fiber drum / 200 kg steel drum with double PE liner
- Small pack: 1 kg / 5 kg aluminum foil bag for lab & sample
- Custom: packaging size and labeling per customer requirement
- Lead time: in-stock items ship within 3-5 business days
- Documents: COA, MSDS / SDS, TDS provided with every shipment
- Global: air, sea (FCL / LCL) and express to 80+ countries
Storage & Handling
Store in a cool, dry, well-ventilated place away from heat, direct sunlight and incompatible materials. Keep container tightly closed. Use appropriate personal protective equipment and refer to the SDS for full safety guidance before handling.
Frequently Asked Questions
Yes. A batch-specific COA and free or charged sample are available on request before bulk ordering.
Yes. We offer custom grade, particle size and purity adjustment based on your application and order volume.
MOQ depends on the product; small quantities are supported for R&D and trial runs.
Every batch is tested in-house and retains full traceability from raw material to finished goods.
Why Choose Jinan Shenghe Chemical
Request a Quote
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About Jinan Shenghe Chemical Co., Ltd.
Jinan Shenghe Chemical Co., Ltd.
We are a professional chemical supplier based in Jinan, China. Since 2013, we have been connecting manufacturers and global B2B buyers with reliable sourcing, quality-controlled products and efficient logistics.
Our business covers food & feed additives, fine chemicals, pharmaceutical intermediates, eco-materials, coatings and specialty chemicals — all non-hazardous and compliant with our licensed scope.